IST1 anticorps (AA 172-284)

N° du produit ABIN7157138

Cet anticorps Lapin Polyclonal détecte spécifiquement IST1 dans ELISA, IHC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour IST1 anticorps (AA 172-284) (ABIN7157138)

Antigène: IST1 (Increased Sodium Tolerance 1 Homolog (IST1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IST1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-IST1 anticorps

Épitope: AA 172-284

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human IST1 homolog protein (172-284AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur IST1

Antigène: IST1 (Increased Sodium Tolerance 1 Homolog (IST1))

Autre désignation: IST1

Sujet:

Background: ESCRT-III-like protein involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells (PubMed:19129479, PubMed:19129480). During late anaphase, involved in nuclear envelope reassembly and mitotic spindle disassembly together with the ESCRT-III complex: IST1 acts by mediating the recruitment of SPAST to the nuclear membrane, leading to microtubule severing (PubMed:26040712). Regulates early endosomal tubulation together with the ESCRT-III complex by mediating the recruitment of SPAST (PubMed:23897888).

Aliases: hIST1 antibody, Increased sodium tolerance 1 antibody, Increased sodium tolerance 1 homolog antibody, IST1 homolog antibody, IST1_HUMAN antibody, KIAA0174 antibody, MAPK activating protein PM28 antibody, MGC117220 antibody, MGC128433 antibody, Putative MAPK-activating protein PM28 antibody

UniProt: P53990

Pathways: Regulation of Cell Size