KLHL12 anticorps (AA 1-220) (Biotin)

N° du produit ABIN7157268

L’anticorps Lapin Polyclonal anti-KLHL12 a été validé pour ELISA. Il convient pour détecter KLHL12 dans des échantillons de Humain.

Aperçu rapide pour KLHL12 anticorps (AA 1-220) (Biotin) (ABIN7157268)

Antigène: KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLHL12 est conjugé à/à la Biotin

Application: ELISA

Détail du produit anti-KLHL12 anticorps (Biotin)

Épitope: AA 1-220

Fonction: KLHL12 Antibody, Biotin conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Kelch-like protein 12 protein (1-220AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur KLHL12

Antigène: KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))

Autre désignation: KLHL12

Sujet:

Background: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a negative regulator of Wnt signaling pathway and ER-Golgi transport. The BCR(KLHL12) complex is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division: BCR(KLHL12) acts by mediating monoubiquitination of SEC31 (SEC31A or SEC31B). As part of the BCR(KLHL12) complex, also acts as a negative regulator of the Wnt signaling pathway by mediating ubiquitination and subsequent proteolysis of DVL3. The BCR(KLHL12) complex also mediates polyubiquitination of DRD4, without leading to degradation of DRD4.

Aliases: C3IP1 antibody, CUL3 interacting protein 1 antibody, CUL3-interacting protein 1 antibody, DKIR antibody, DKIR homolog antibody, FLJ27152 antibody, hDKIR antibody, Kelch like 12 (Drosophila) antibody, Kelch like 12 antibody, Kelch like 12 variant antibody, Kelch like protein 12 antibody, Kelch like protein C3IP1 antibody, kelch-like family member 12 antibody, Kelch-like protein 12 antibody, KLH12_HUMAN antibody, KLHL 12 antibody, klhl12 antibody, OTTHUMP00000038799 antibody

UniProt: Q53G59