KLHL22 anticorps (AA 2-300)

N° du produit ABIN7157281

Cet anticorps anti-KLHL22 est un anticorps Lapin Polyclonal détectant KLHL22 dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour KLHL22 anticorps (AA 2-300) (ABIN7157281)

Antigène: KLHL22 (Kelch-Like 22 (KLHL22))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLHL22 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-KLHL22 anticorps

Épitope: AA 2-300

Fonction: KLHL22 Antibody

Réactivité croisée: Souris

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Kelch-like protein 22 protein (2-300AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur KLHL22

Antigène: KLHL22 (Kelch-Like 22 (KLHL22))

Autre désignation: KLHL22

Sujet:

Background: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1, leading to PLK1 dissociation from phosphoreceptor proteins and subsequent removal from kinetochores, allowing silencing of the spindle assembly checkpoint (SAC) and chromosome segregation. Monoubiquitination of PLK1 does not lead to PLK1 degradation.

Aliases: KLHL22Kelch-like protein 22 antibody

UniProt: Q53GT1