KIF14 anticorps (AA 261-531)

N° du produit ABIN7157595

Détail du produit anti-KIF14 anticorps

Antigène: KIF14 (Kinesin Family Member 14 (KIF14))

Épitope: AA 261-531

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIF14 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Kinesin-like protein KIF14 protein (261-531AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur KIF14

Antigène: KIF14 (Kinesin Family Member 14 (KIF14))

Autre désignation: KIF14 (KIF14 Produits)

Synonymes: anticorps wu:fi16h07, anticorps si:dkey-39e8.3, anticorps KIF14, anticorps D1Ertd367e, anticorps E130203M01, anticorps kinesin family member 14, anticorps kinesin-like protein KIF14, anticorps KIF14, anticorps kif14, anticorps LOC100641544, anticorps Kif14

Sujet:

Background: Microtubule motor protein that binds to microtubules with high affinity through each tubulin heterodimer and has an ATPase activity (By similarity). Plays a role in many processes like cell division, cytokinesis and also in cell proliferation and apoptosis (PubMed:24784001, PubMed:16648480). During cytokinesis, targets to central spindle and midbody through its interaction with PRC1 and CIT respectively (PubMed:16431929). Regulates cell growth through regulation of cell cycle progression and cytokinesis (PubMed:24854087). During cell cycle progression acts through SCF-dependent proteasomal ubiquitin-dependent protein catabolic process which controls CDKN1B degradation, resulting in positive regulation of cyclins, including CCNE1, CCND1 and CCNB1 (PubMed:24854087). During late neurogenesis, regulates the cerebellar, cerebral cortex and olfactory bulb development through regulation of apoptosis, cell proliferation and cell division (By similarity). Also is required for chromosome congression and alignment during mitotic cell cycle process (PubMed:15843429). Regulates cell spreading, focal adhesion dynamics, and cell migration through its interaction with RADIL resulting in regulation of RAP1A-mediated inside-out integrin activation by tethering RADIL on microtubules (PubMed:23209302).

Aliases: KIAA0042 antibody, KIF 14 antibody, KIF14 antibody, KIF14_HUMAN antibody, Kinesin Family Member 14 antibody, Kinesin like protein KIF14 antibody, Kinesin-like protein KIF14 antibody, MGC142302 antibody

UniProt: Q15058