NDC80 anticorps (AA 1-249)

N° du produit ABIN7157661

L’anticorps Lapin Polyclonal anti-NDC80 a été validé pour ELISA et IHC. Il convient pour détecter NDC80 dans des échantillons de Humain.

Aperçu rapide pour NDC80 anticorps (AA 1-249) (ABIN7157661)

Antigène: NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NDC80 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-NDC80 anticorps

Épitope: AA 1-249

Fonction: NDC80 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Kinetochore protein NDC80 homolog protein (1-249AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur NDC80

Antigène: NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))

Autre désignation: NDC80

Sujet:

Background: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:9315664, PubMed:12351790, PubMed:14654001, PubMed:14699129, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:16732327). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:15548592). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020).

Aliases: from Entrez Gene , antibody, HEC antibody, Highly expressed in cancer antibody, Highly expressed in cancer protein antibody, Highly expressed in cancer rich in leucine heptad repeats antibody, HsHec1 antibody, hsNDC80 antibody, Kinetochore associated 2 antibody, Kinetochore associated protein 2 antibody, Kinetochore protein Hec1 antibody, Kinetochore protein NDC80 homolog antibody, Kinetochore-associated protein 2 antibody, KNTC2 antibody, ndc80 antibody, NDC80 homolog kinetochore complex component antibody, NDC80 kinetochore complex component homolog antibody, NDC80, S. cerevisiae, homolog of antibody, NDC80_HUMAN antibody, Retinoblastoma associated protein HEC antibody, Retinoblastoma-associated protein HEC antibody, TID3 antibody

UniProt: O14777

Pathways: Maintenance of Protein Location