KARS anticorps (AA 101-400)

N° du produit ABIN7158683

Détail du produit anti-KARS anticorps

Antigène: KARS (Lysyl-tRNA Synthetase (KARS))

Épitope: AA 101-400

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KARS est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Lysine--tRNA ligase protein (101-400AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur KARS

Antigène: KARS (Lysyl-tRNA Synthetase (KARS))

Autre désignation: KARS (KARS Produits)

Synonymes: anticorps CG12141, anticorps Dmel\\CG12141, anticorps KRS, anticorps LysRS, anticorps cb530, anticorps wu:fa16h02, anticorps zgc:92483, anticorps kars, anticorps MGC53345, anticorps kars2, anticorps krs, anticorps krs-1, anticorps KARS, anticorps Tb06.28P18.190, anticorps CMTRIB, anticorps DFNB89, anticorps KARS1, anticorps KARS2, anticorps AA589550, anticorps AL024334, anticorps AL033315, anticorps AL033367, anticorps D8Ertd698e, anticorps D8Wsu108e, anticorps mKIAA0070, anticorps Lysyl-tRNA synthetase, anticorps lysyl-tRNA synthetase, anticorps lysyl-tRNA synthetase S homeolog, anticorps lysyl-tRNA synthetase L homeolog, anticorps LysRS, anticorps kars, anticorps kars.S, anticorps kars.L, anticorps Bm1_16500, anticorps lysS, anticorps Taci_1118, anticorps Tpau_1737, anticorps Arch_0261, anticorps Trad_2960, anticorps Spirs_3699, anticorps KARS, anticorps LOC100280510, anticorps Tb927.6.1510, anticorps Kars

Sujet:

Background: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA (PubMed:9278442, PubMed:18029264, PubMed:18272479). When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages (PubMed:15851690). Catalyzes the synthesis of the signaling molecule diadenosine tetraphosphate (Ap4A), and thereby mediates disruption of the complex between HINT1 and MITF and the concomitant activation of MITF transcriptional activity (PubMed:5338216, PubMed:14975237, PubMed:19524539, PubMed:23159739). (Microbial infection) Interacts with HIV-1 virus GAG protein, facilitating the selective packaging of tRNA3(Lys), the primer for reverse transcription initiation.

Aliases: CMTRIB antibody, DFNB89 antibody, EC 6.1.1.6 antibody, KARS 1 antibody, KARS 2 antibody, KARS antibody, KARS1 antibody, KARS2 antibody, KIAA0070 antibody, KRS antibody, Lysine tRNA ligase antibody, Lysine--tRNA ligase antibody, LysRS antibody, Lysyl tRNA synthetase antibody, Lysyl-tRNA synthetase antibody, SYK_HUMAN antibody

UniProt: Q15046