MRGPRX2 anticorps (AA 286-330)
Aperçu rapide pour MRGPRX2 anticorps (AA 286-330) (ABIN7159013)
Antigène
Voir toutes MRGPRX2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 286-330
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Réactivité croisée
- Humain, Souris
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Purification
- >95%, Protein G purified
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Immunogène
- Recombinant Human Mas-related G-protein coupled receptor member X2 protein (286-330AA)
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Isotype
- IgG
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Indications d'application
- Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))
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Autre désignation
- MRGPRX2
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Sujet
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Background: Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core (PubMed:25517090). Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction. Acts as a receptor for a number of other ligands, including peptides and alkaloids, such as cortistatin-14, proadrenomedullin N-terminal peptides PAMP-12 and, at lower extent, PAMP-20, antibacterial protein LL-37, PMX-53 peptide, beta-defensins, and complanadine A.
Aliases: G protein coupled receptor MRGX 2 antibody, G protein coupled receptor MRGX2 antibody, Mas related G protein coupled receptor member X2 antibody, Mas related gene MRGX 2 antibody, Mas related gene MRGX2 antibody, MAS related GPR member X2 antibody, Mas-related G-protein coupled receptor member X antibody, Mas-related G-protein coupled receptor member X2 antibody, MRGPRX 2 antibody, MRGPRX2 antibody, MRGX 2 antibody, MRGX2 antibody, MRGX2_HUMAN antibody
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UniProt
- Q96LB1
Antigène
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