C20orf72 anticorps (AA 81-260)

N° du produit ABIN7159874

Cet anticorps Lapin Polyclonal détecte spécifiquement C20orf72 dans ELISA, WB et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour C20orf72 anticorps (AA 81-260) (ABIN7159874)

Antigène: C20orf72 (MGME1) (Mitochondrial Genome Maintenance Exonuclease 1 (MGME1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C20orf72 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-C20orf72 anticorps

Épitope: AA 81-260

Fonction: MGME1 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Mitochondrial genome maintenance exonuclease 1 protein (81-260AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur C20orf72

Antigène: C20orf72 (MGME1) (Mitochondrial Genome Maintenance Exonuclease 1 (MGME1))

Autre désignation: MGME1

Sujet:

Background: Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5\'-3\' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells.

Aliases: MGME1 antibody, C20orf72 antibody, DDK1Mitochondrial genome maintenance exonuclease 1 antibody, EC 3.1.-.- antibody

UniProt: Q9BQP7