CHCHD4 anticorps (AA 1-142) (Biotin)

N° du produit ABIN7159924

Cet anticorps anti-CHCHD4 est un anticorps Lapin Polyclonal détectant CHCHD4 dans ELISA. Adapté pour Humain.

Aperçu rapide pour CHCHD4 anticorps (AA 1-142) (Biotin) (ABIN7159924)

Antigène: CHCHD4 (Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 4 (CHCHD4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHCHD4 est conjugé à/à la Biotin

Application: ELISA

Détail du produit anti-CHCHD4 anticorps (Biotin)

Épitope: AA 1-142

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Mitochondrial intermembrane space import and assembly protein 40 protein (1-142AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CHCHD4

Antigène: CHCHD4 (Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 4 (CHCHD4))

Autre désignation: CHCHD4

Sujet:

Background: Functions as chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COX17. Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS. Reduced CHCHD4/MIA40 is then reoxidized by GFER/ERV1 via a disulfide relay system.

Aliases: CHCHD4 antibody, MIA40Mitochondrial intermembrane space import and assembly protein 40 antibody, Coiled-coil-helix-coiled-coil-helix domain-containing protein 4 antibody

UniProt: Q8N4Q1