BUB3 anticorps (AA 6-217)

N° du produit ABIN7160076

Détail du produit anti-BUB3 anticorps

Antigène: BUB3 (Budding Uninhibited By Benzimidazoles 3 Homolog (Yeast) (BUB3))

Épitope: AA 6-217

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BUB3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Mitotic checkpoint protein BUB3 protein (6-217AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur BUB3

Antigène: BUB3 (Budding Uninhibited By Benzimidazoles 3 Homolog (Yeast) (BUB3))

Autre désignation: BUB3 (BUB3 Produits)

Synonymes: anticorps BUB3L, anticorps hBUB3, anticorps Aa2-050, anticorps xbub3, anticorps AU019800, anticorps AU021329, anticorps AU043350, anticorps AW146323, anticorps C78067, anticorps BUB3, mitotic checkpoint protein, anticorps BUB3 mitotic checkpoint protein, anticorps BUB3 mitotic checkpoint protein L homeolog, anticorps BUB3, anticorps Bub3, anticorps bub3.L

Sujet:

Background: Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. Regulates chromosome segregation during oocyte meiosis. The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome (APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1.

Aliases: Aa2-050 antibody, AU019800 antibody, AU021329 antibody, AU043350 antibody, AW146323 antibody, BUB 3 antibody, BUB 3L antibody, BUB3 (budding uninhibited by benzimidazoles 3, yeast) homolog antibody, bub3 antibody, BUB3 budding uninhibited by benzimidazoles 3 homolog antibody, BUB3 mitotic checkpoint protein antibody, BUB3_HUMAN antibody, BUB3L antibody, Budding uninhibited by benomyl antibody, Budding uninhibited by benzimidazoles 3 antibody, Budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae) antibody, Budding uninhibited by benzimidazoles 3 homolog (yeast) antibody, Budding uninhibited by benzimidazoles 3 homolog antibody, Budding uninhibited by benzimidazoles 3, S. cerevisiae, homolog of antibody, C78067 antibody, hBUB3 antibody, Mitotic checkpoint component antibody, Mitotic checkpoint protein bub3 antibody, OTTHUMP00000020679 antibody, OTTHUMP00000020680 antibody, WD repeat type I transmembrane protein A72.5 antibody

UniProt: O43684

Pathways: Maintenance of Protein Location