MLF1 anticorps (AA 1-268)
Aperçu rapide pour MLF1 anticorps (AA 1-268) (ABIN7160476)
Antigène
Voir toutes MLF1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-268
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Fonction
- MLF1 Antibody
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Réactivité croisée
- Souris
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Purification
- Antigen Affinity Purified
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Immunogène
- Recombinant Human Myeloid leukemia factor 1 protein (1-268AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MLF1 (Myeloid Leukemia Factor 1 (MLF1))
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Autre désignation
- MLF1
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Sujet
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Background: Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
Aliases: Hls7 antibody, MLF1 antibody, MLF1_HUMAN antibody, Myelodysplasia myeloid leukemia factor 1 antibody, Myelodysplasia-myeloid leukemia factor 1 antibody, Myeloid leukemia factor 1 antibody, myeloid leukemia factor 1 variant 1 antibody, myeloid leukemia factor 1 variant 2 antibody, myeloid leukemia factor 1 variant 3 antibody
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UniProt
- P58340
Antigène
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