MYOC anticorps (AA 183-294) (Biotin)

N° du produit ABIN7160497

Cet anticorps anti-MYOC est un anticorps Lapin Polyclonal détectant MYOC dans ELISA. Adapté pour Humain.

Aperçu rapide pour MYOC anticorps (AA 183-294) (Biotin) (ABIN7160497)

Antigène: MYOC (Myocilin (MYOC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYOC est conjugé à/à la Biotin

Application: ELISA

Détail du produit anti-MYOC anticorps (Biotin)

Épitope: AA 183-294

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Myocilin protein (183-294AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MYOC

Antigène: MYOC (Myocilin (MYOC))

Autre désignation: MYOC

Sujet:

Background: Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion, cell-matrix adhesion, cytoskeleton organization and cell migration. Promotes substrate adhesion, spreading and formation of focal contacts. Negatively regulates cell-matrix adhesion and stress fiber assembly through Rho protein signal transduction. Modulates the organization of actin cytoskeleton by stimulating the formation of stress fibers through interactions with components of Wnt signaling pathways. Promotes cell migration through activation of PTK2 and the downstream phosphatidylinositol 3-kinase signaling. Plays a role in bone formation and promotes osteoblast differentiation in a dose-dependent manner through mitogen-activated protein kinase signaling. Mediates myelination in the peripheral nervous system through ERBB2/ERBB3 signaling. Plays a role as a regulator of muscle hypertrophy through the components of dystrophin-associated protein complex. Involved in positive regulation of mitochondrial depolarization. Plays a role in neurite outgrowth. May participate in the obstruction of fluid outflow in the trabecular meshwork.

Aliases: GLC1A antibody, GPOA antibody, JOAG antibody, JOAG1 antibody, Mutated trabecular meshwork-induced glucocorticoid response protein antibody, MYOC antibody, MYOC_HUMAN antibody, Myocilin antibody, Myocilin, trabecular meshwork inducible glucocorticoid antibody, TIGR antibody, Trabecular meshwork induced glucocorticoid response protein antibody, Trabecular meshwork-induced glucocorticoid response protein antibody

UniProt: Q99972