MTM1 anticorps (AA 484-603)

N° du produit ABIN7160627

Cet anticorps Lapin Polyclonal détecte spécifiquement MTM1 dans WB, ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour MTM1 anticorps (AA 484-603) (ABIN7160627)

Antigène: MTM1 (Myotubularin 1 (MTM1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MTM1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-MTM1 anticorps

Épitope: AA 484-603

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Myotubularin protein (484-603AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MTM1

Antigène: MTM1 (Myotubularin 1 (MTM1))

Autre désignation: MTM1

Sujet:

Background: Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not for myogenesis.

Aliases: AF073996 antibody, CG2 antibody, CNM antibody, KIAA4176 antibody, mKIAA4176 antibody, Mtm antibody, Mtm1 antibody, MTM1_HUMAN antibody, MTMX antibody, Myotubular myopathy 1 antibody, Myotubularin antibody, XLMTM antibody

UniProt: Q13496

Pathways: Inositol Metabolic Process, Skeletal Muscle Fiber Development