METTL14 anticorps (AA 24-206)

N° du produit ABIN7160801

Détail du produit anti-METTL14 anticorps

Antigène: METTL14 (Methyltransferase Like 14 (METTL14))

Épitope: AA 24-206

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp METTL14 est non-conjugé

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human N6-adenosine-methyltransferase subunit METTL14 protein (24-206AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur METTL14

Antigène: METTL14 (Methyltransferase Like 14 (METTL14))

Autre désignation: METTL14 (METTL14 Produits)

Synonymes: anticorps RGD1304822, anticorps G430022H21Rik, anticorps mKIAA1627, anticorps zgc:77296, anticorps methyltransferase like 14, anticorps methyltransferase like 14 L homeolog, anticorps Mettl14, anticorps mettl14.L, anticorps METTL14, anticorps mettl14

Sujet:

Background: N6-methyltransferase that methylates adenosine residues of some mRNAs and acts as a regulator of the circadian clock and differentiation of embryonic stem cells. N6-methyladenosine (m6A), which takes place at the 5\'-[AG]GAC-3\' consensus sites of some mRNAs, plays a role in the efficiency of mRNA splicing, processing and mRNA stability (PubMed:24316715, PubMed:24407421, PubMed:25719671). M6A regulates the length of the circadian clock: acts as a early pace-setter in the circadian loop. M6A also acts as a regulator of mRNA stability: in embryonic stem cells (ESCs), m6A methylation of mRNAs encoding key naive pluripotency-promoting transcripts results in transcript destabilization (By similarity).

Aliases: KIAA1627 antibody, MET14_HUMAN antibody, Methyltransferase like 14 antibody, Methyltransferase-like protein 14 antibody, METTL14 antibody, N6-adenosine-methyltransferase subunit METTL14 antibody, OTTHUMP00000219837 antibody

UniProt: Q9HCE5