NCR3 anticorps (AA 19-135) (HRP)

N° du produit ABIN7161083

Cet anticorps Lapin Polyclonal détecte spécifiquement NCR3 dans ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour NCR3 anticorps (AA 19-135) (HRP) (ABIN7161083)

Antigène: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCR3 est conjugé à/à la HRP

Application: ELISA

Détail du produit anti-NCR3 anticorps (HRP)

Épitope: AA 19-135

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Natural cytotoxicity triggering receptor 3 protein (19-135AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur NCR3

Antigène: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Autre désignation: NCR3

Sujet:

Background: Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation.

Aliases: 1C7 antibody, Activating natural killer receptor p30 antibody, Activating NK A1 receptor antibody, CD337 antibody, CD337 antigen antibody, LY117 antibody, Lymphocyte antigen 117 antibody, MALS antibody, Natural cytotoxicity triggering receptor 3 antibody, Natural killer cell p30 related protein antibody, Natural killer cell p30-related protein antibody, Ncr3 antibody, NCTR3_HUMAN antibody, NK-p30 antibody, NKp30 antibody

UniProt: O14931

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process