UBA3 anticorps (Catalytic Subunit)

N° du produit ABIN7161136

Détail du produit anti-UBA3 anticorps

Antigène: UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))

Épitope: AA 234-463, Catalytic Subunit

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBA3 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human NEDD8-activating enzyme E1 catalytic subunit protein (234-463AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur UBA3

Antigène: UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))

Autre désignation: UBA3 (UBA3 Produits)

Synonymes: anticorps UBE1C, anticorps hUBA3, anticorps Ube1c, anticorps ube1c, anticorps wu:fb75e04, anticorps wu:fc37b11, anticorps zgc:55528, anticorps A830034N06Rik, anticorps AI256736, anticorps AI848246, anticorps AW546539, anticorps ubiquitin like modifier activating enzyme 3, anticorps ubiquitin-like modifier activating enzyme 3, anticorps ubiquitin like modifier activating enzyme 3 S homeolog, anticorps UBA3, anticorps Uba3, anticorps uba3, anticorps uba3.S

Sujet:

Background: Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down-regulates steroid receptor activity. Necessary for cell cycle progression.

Aliases: DKFZp566J164 antibody, EC 6.3.2. antibody, hUba3 antibody, MGC22384 antibody, NEDD8 activating enzyme E1 catalytic subunit antibody, NEDD8 activating enzyme E1C antibody, Nedd8 activating enzyme hUba3 antibody, NEDD8-activating enzyme E1 catalytic subunit antibody, NEDD8-activating enzyme E1C antibody, uba3 antibody, UBA3 ubiquitin activating enzyme E1 homolog antibody, UBA3_HUMAN antibody, UBE1C antibody, Ubiquitin activating enzyme 3 antibody, Ubiquitin activating enzyme E1C antibody, Ubiquitin-activating enzyme 3 antibody, Ubiquitin-activating enzyme E1C antibody, Ubiquitin-like modifier-activating enzyme 3 antibody

UniProt: Q8TBC4