NEUROD1 anticorps (AA 154-356)

N° du produit ABIN7161282

L’anticorps Lapin Polyclonal anti-NEUROD1 a été validé pour WB, ELISA et IF. Il convient pour détecter NEUROD1 dans des échantillons de Humain.

Aperçu rapide pour NEUROD1 anticorps (AA 154-356) (ABIN7161282)

Antigène: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NEUROD1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-NEUROD1 anticorps

Épitope: AA 154-356

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Neurogenic differentiation factor 1 protein (154-356AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:200-1:2000, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur NEUROD1

Antigène: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Autre désignation: NEUROD1

Sujet:

Background: Acts as a transcriptional activator: mediates transcriptional activation by binding to E box-containing promoter consensus core sequences 5\\\'-CANNTG-3\\\'. Associates with the p300/CBP transcription coactivator complex to stimulate transcription of the secretin gene as well as the gene encoding the cyclin-dependent kinase inhibitor CDKN1A. Contributes to the regulation of several cell differentiation pathways, like those that promote the formation of early retinal ganglion cells, inner ear sensory neurons, granule cells forming either the cerebellum or the dentate gyrus cell layer of the hippocampus, endocrine islet cells of the pancreas and enteroendocrine cells of the small intestine. Together with PAX6 or SIX3, is required for the regulation of amacrine cell fate specification. Also required for dendrite morphogenesis and maintenance in the cerebellar cortex. Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis (By similarity).

Aliases: atonal antibody, basic helix loop helix transcription factor antibody, BETA 2 antibody, Beta cell E box transactivator 2 antibody, BETA2 antibody, BHF 1 antibody, BHF1 antibody, bHLHa3 antibody, class A basic helix loop helix protein 3 antibody, Class A basic helix-loop-helix protein 3 antibody, MODY 6 antibody, MODY6 antibody, NDF1_HUMAN antibody, NeuroD antibody, NeuroD1 antibody, Neurogenic differentiation 1 antibody, Neurogenic differentiation factor 1 antibody, neurogenic helix loop helix protein NEUROD antibody, Neuronal differentiation 1 antibody

UniProt: Q13562

Pathways: Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis