NMNAT1 anticorps (AA 1-279)

N° du produit ABIN7161578

Cet anticorps Lapin Polyclonal détecte spécifiquement NMNAT1 dans IHC et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour NMNAT1 anticorps (AA 1-279) (ABIN7161578)

Antigène: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NMNAT1 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-NMNAT1 anticorps

Épitope: AA 1-279

Fonction: NMNAT1 Antibody

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 protein (1-279AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur NMNAT1

Antigène: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Autre désignation: NMNAT1

Sujet:

Background: Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form, nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, prefers NAD(+) and NaAD as substrates and degrades NADH, nicotinic acid adenine dinucleotide phosphate (NHD) and nicotinamide guanine dinucleotide (NGD) less effectively. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NaADP(+). Protects against axonal degeneration following mechanical or toxic insults.

Aliases: EC 2.7.7.1 antibody, LCA9 antibody, Leber's congenital amaurosis 9 antibody, NaMN adenylyltransferase 1 antibody, nicotinamide nucleotide adenylyltransferase 1 antibody, Nicotinamide-nucleotide adenylyltransferase 1 antibody, Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 antibody, nicotinate nucleotide adenylyltransferase 1 antibody, Nicotinate-nucleotide adenylyltransferase 1 antibody, NMN adenylyltransferase 1 antibody, NMN/NaMN adenylyltransferase 1 antibody, NMNA1_HUMAN antibody, Nmnat 1 antibody, Nmnat1 antibody, OTTHUMP00000001731 antibody, OTTHUMP00000001732 antibody, OTTHUMP00000035892 antibody, PNAT 1 antibody, PNAT1 antibody, pyridine nucleotide adenylyltransferase 1 antibody

UniProt: Q9HAN9