NCOA6 anticorps (AA 285-504)

N° du produit ABIN7161865

Cet anticorps anti-NCOA6 est un anticorps Lapin Polyclonal détectant NCOA6 dans ELISA et IHC. Adapté pour Humain.

Aperçu rapide pour NCOA6 anticorps (AA 285-504) (ABIN7161865)

Antigène: NCOA6 (Nuclear Receptor Coactivator 6 (NCOA6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCOA6 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-NCOA6 anticorps

Épitope: AA 285-504

Fonction: NCOA6 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Nuclear receptor coactivator 6 protein (285-504AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur NCOA6

Antigène: NCOA6 (Nuclear Receptor Coactivator 6 (NCOA6))

Autre désignation: NCOA6

Sujet:

Background: Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist- and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins.

Aliases: NCOA6 antibody, AIB3 antibody, KIAA0181 antibody, RAP250 antibody, TRBP antibody, Nuclear receptor coactivator 6 antibody, Activating signal cointegrator 2 antibody, ASC-2 antibody, Amplified in breast cancer protein 3 antibody, Cancer-amplified transcriptional coactivator ASC-2 antibody, Nuclear receptor coactivator RAP250 antibody, NRC RAP250 antibody, Nuclear receptor-activating protein antibody, 250 kDa antibody, Peroxisome proliferator-activated receptor-interacting protein antibody, PPAR-interacting protein antibody, PRIP antibody, Thyroid hormone receptor-binding protein antibody

UniProt: Q14686

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha