SIN3B anticorps (AA 705-769) (Biotin)
Aperçu rapide pour SIN3B anticorps (AA 705-769) (Biotin) (ABIN7162488)
Antigène
Voir toutes SIN3B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 705-769
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Réactivité croisée
- Humain
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Purification
- >95%, Protein G purified
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Immunogène
- Recombinant Human Paired amphipathic helix protein Sin3b protein (705-769AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))
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Autre désignation
- SIN3B
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Sujet
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Background: Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression.
Aliases: SIN3B antibody, KIAA0700 antibody, Paired amphipathic helix protein Sin3b antibody, Histone deacetylase complex subunit Sin3b antibody, Transcriptional corepressor Sin3b antibody
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UniProt
- O75182
Antigène
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