PLIN5 anticorps (AA 305-453)

N° du produit ABIN7162899

Détail du produit anti-PLIN5 anticorps

Antigène: PLIN5 (Perilipin 5 (PLIN5))

Épitope: AA 305-453

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLIN5 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Perilipin-5 protein (305-453AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PLIN5

Antigène: PLIN5 (Perilipin 5 (PLIN5))

Autre désignation: PLIN5 (PLIN5 Produits)

Synonymes: anticorps LSDA5, anticorps LSDP5, anticorps MLDP, anticorps OXPAT, anticorps 2310076L09Rik, anticorps AI415325, anticorps AW109675, anticorps Lsdp5, anticorps PAT-1, anticorps perilipin 5, anticorps PLIN5, anticorps Plin5

Sujet:

Background: Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation. In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets. Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2. Also increases lipolysis through interaction with LIPE and upon PKA-mediated phosphorylation of LIPE (By similarity).

Aliases: Lipid storage droplet protein 5 antibody, LSDA5 antibody, MLDP antibody, OXPAT antibody, Perilipin 5 antibody, Perilipin-5 antibody, PLIN5 antibody, PLIN5_HUMAN antibody

UniProt: Q00G26