PIK3C3 anticorps (Catalytic Subunit)

N° du produit ABIN7163159

Cet anticorps Lapin Polyclonal détecte spécifiquement PIK3C3 dans WB, ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour PIK3C3 anticorps (Catalytic Subunit) (ABIN7163159)

Antigène: PIK3C3 (Phosphoinositide-3-Kinase, Class 3 (PIK3C3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIK3C3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-PIK3C3 anticorps

Épitope: AA 700-850, Catalytic Subunit

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Phosphatidylinositol 3-kinase catalytic subunit type 3 protein (700-850AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PIK3C3

Antigène: PIK3C3 (Phosphoinositide-3-Kinase, Class 3 (PIK3C3))

Autre désignation: PIK3C3

Sujet:

Background: Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate, different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123, PubMed:20208530). Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes (By similarity).

Aliases: hVps34 antibody, MGC61518 antibody, Phosphatidylinositol 3 kinase catalytic subunit type 3 antibody, Phosphatidylinositol 3 kinase class 3 antibody, Phosphatidylinositol 3 kinase p100 subunit antibody, Phosphatidylinositol 3-kinase catalytic subunit type 3 antibody, Phosphatidylinositol 3-kinase p100 subunit antibody, Phosphoinositide 3 kinase class 3 antibody, Phosphoinositide-3-kinase class 3 antibody, PI3 kinase type 3 antibody, PI3-kinase type 3 antibody, PI3K type 3 antibody, Pik3c3 antibody, PK3C3_HUMAN antibody, PtdIns 3 kinase type 3 antibody, PtdIns-3-kinase type 3 antibody, Vps 34 antibody, Vps34 antibody

UniProt: Q8NEB9

Pathways: AMPK Signaling, Activation of Innate immune Response, Inositol Metabolic Process, Toll-Like Receptors Cascades, Autophagy