CYP4F2 anticorps (AA 268-373)

N° du produit ABIN7163434

Cet anticorps anti-CYP4F2 Polyclonal Lapin (ABIN7163434) détecte spécifiquement CYP4F2 dans ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CYP4F2 anticorps (AA 268-373) (ABIN7163434)

Antigène: CYP4F2 (Cytochrome P450, Family 4, Subfamily F, Polypeptide 2 (CYP4F2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP4F2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-CYP4F2 anticorps

Épitope: AA 268-373

Fonction: CYP4F2 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Phylloquinone omega-hydroxylase CYP4F2 protein (268-373AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CYP4F2

Antigène: CYP4F2 (Cytochrome P450, Family 4, Subfamily F, Polypeptide 2 (CYP4F2))

Autre désignation: CYP4F2

Sujet:

Background: Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone), and menaquinone-4 (MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation (PubMed:19297519, PubMed:24138531). Also shows arachidonic acid omega-hydroxylase activity in kidney, by mediating conversion of arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE), possibly influencing blood pressure control (PubMed:10660572, PubMed:17341693, PubMed:18574070). Also acts as a leukotriene-B(4) omega-hydroxylase by mediating conversion of leukotriene-B(4) (LTB4) to its omega-hydroxylated metabolite 20-hydroxyleukotriene-B(4) (20-OH LTB4) (PubMed:8026587, PubMed:9799565).

Aliases: CYP4F2Cytochrome P450 4F2 antibody, EC 1.14.14.1 antibody, 20-hydroxyeicosatetraenoic acid synthase antibody, 20-HETE synthase antibody, Arachidonic acid omega-hydroxylase antibody, CYPIVF2 antibody, Cytochrome P450-LTB-omega antibody, Docosahexaenoic acid omega-hydroxylase antibody, EC 1.14.14.79 antibody, Leukotriene-B(4) 20-monooxygenase 1 antibody, Leukotriene-B(4) omega-hydroxylase 1 antibody, EC 1.14.14.94 antibody, Phylloquinone omega-hydroxylase CYP4F2 antibody, EC 1.14.14.78 antibody

UniProt: P78329

Pathways: Monocarboxylic Acid Catabolic Process