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PITX3 anticorps (AA 10-200) (FITC)

PITX3 Reactivité: Humain Hôte: Lapin Polyclonal FITC
N° du produit ABIN7163471
  • Antigène Voir toutes PITX3 Anticorps
    PITX3 (Pituitary Homeobox 3 (PITX3))
    Épitope
    • 15
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 10-200
    Reactivité
    • 25
    • 22
    • 21
    • 19
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    Humain
    Hôte
    • 37
    • 1
    Lapin
    Clonalité
    • 37
    • 1
    Polyclonal
    Conjugué
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PITX3 est conjugé à/à la FITC
    Application
    Veuillez nous consulter SVP
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Pituitary homeobox 3 protein (10-200AA)
    Isotype
    IgG
    Top Product
    Discover our top product PITX3 Anticorps primaire
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    PITX3 (Pituitary Homeobox 3 (PITX3))
    Autre désignation
    PITX3 (PITX3 Produits)
    Synonymes
    anticorps CTPP4, anticorps CTRCT11, anticorps PTX3, anticorps pitx3, anticorps Ptx3, anticorps ak, anticorps zgc:109716, anticorps pitx3-A, anticorps xPitx3, anticorps paired like homeodomain 3, anticorps paired-like homeodomain 3, anticorps paired like homeodomain 3 L homeolog, anticorps paired-like homeodomain transcription factor 3, anticorps paired-like homeodomain transcription factor Pitx3, anticorps PITX3, anticorps Pitx3, anticorps pitx3.L, anticorps pitx3
    Sujet

    Background: Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. In addition to its importance during development, it also has roles in the long-term survival and maintenance of the mdDA neurons. Activates NR4A2/NURR1-mediated transcription of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons. Acts by decreasing the interaction of NR4A2/NURR1 with the corepressor NCOR2/SMRT which acts through histone deacetylases (HDACs) to keep promoters of NR4A2/NURR1 target genes in a repressed deacetylated state. Essential for the normal lens development and differentiation. Plays a critical role in the maintenance of mitotic activity of lens epithelial cells, fiber cell differentiation and in the control of the temporal and spatial activation of fiber cell-specific crystallins. Positively regulates FOXE3 expression and negatively regulates PROX1 in the anterior lens epithelium, preventing activation of CDKN1B/P27Kip1 and CDKN1C/P57Kip2 and thus maintains lens epithelial cells in cell cycle (By similarity).

    Aliases: Homeobox protein PITX 3 antibody, Homeobox protein PITX3 antibody, MGC12766 antibody, Paired like homeodomain transcription factor 3 antibody, Paired-like homeodomain transcription factor 3 antibody, Pituitary homeobox 3 antibody, PITX 3 antibody, Pitx3 antibody, PITX3_HUMAN antibody, PTX 3 antibody, PTX3 antibody

    UniProt
    O75364
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