Plexin B2 anticorps (AA 1080-1200)

N° du produit ABIN7163708

Cet anticorps Lapin Polyclonal détecte spécifiquement Plexin B2 dans ELISA, WB et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour Plexin B2 anticorps (AA 1080-1200) (ABIN7163708)

Antigène: Plexin B2 (PLXNB2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Plexin B2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Plexin B2 anticorps

Épitope: AA 1080-1200

Fonction: PLXNB2 Antibody

Réactivité croisée: Souris

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Plexin-B2 protein (1080-1200AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Plexin B2

Antigène: Plexin B2 (PLXNB2)

Autre désignation: PLXNB2

Sujet:

Background: Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at \\\'Tyr-1248\\\'. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development. Regulates the migration of cerebellar granule cells in the developing brain. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May modulate the activity of RAC1 and CDC42. Down-regulates macrophage migration in wound-healing assays (in vitro) (By similarity).

Aliases: PLXNB2 antibody, KIAA0315 antibody, Plexin-B2 antibody, MM1 antibody

UniProt: O15031

Pathways: Tube Formation