RNF212 anticorps (AA 1-297)
Aperçu rapide pour RNF212 anticorps (AA 1-297) (ABIN7164415)
Antigène
Voir toutes RNF212 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 1-297
-
Fonction
- RNF212 Antibody
-
Purification
- Antigen Affinity Purified
-
Immunogène
- Recombinant Human Probable E3 SUMO-protein ligase RNF212 protein (1-297AA)
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C,-80 °C
-
Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- RNF212 (Ring Finger Protein 212 (RNF212))
-
Autre désignation
- RNF212
-
Sujet
-
Background: SUMO E3 ligase that acts as a regulator of crossing-over during meiosis: required to couple chromosome synapsis to the formation of crossover-specific recombination complexes. Localizes to recombination sites and stabilizes meiosis-specific recombination factors, such as MutS-gamma complex proteins (MSH4 and MSH5) and TEX11. May mediate sumoylation of target proteins MSH4 and/or MSH5, leading to enhance their binding to recombination sites. Acts as a limiting factor for crossover designation and/or reinforcement and plays an antagonist role with CCNB1IP1/HEI10 in the regulation of meiotic recombination (By similarity).
Aliases: FLJ38841 antibody, Hypothetical protein LOC285498 antibody, LOC285498 antibody, OTTHUMP00000147525 antibody, Probable E3 SUMO-protein ligase RNF212 antibody, RING finger protein 212 antibody, RN212_HUMAN antibody, RNF 212 antibody, RNF212 antibody, ZHP3 antibody, ZHP3, C. elegans, homolog of antibody, ZIP3-related protein antibody
-
UniProt
- Q495C1
Antigène
-