BEX2 anticorps (AA 1-128)
Aperçu rapide pour BEX2 anticorps (AA 1-128) (ABIN7165127)
Antigène
Voir toutes BEX2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-128
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Réactivité croisée
- Humain
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Purification
- >95%, Protein G purified
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Immunogène
- Recombinant Human Protein BEX2 protein (1-128AA)
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Isotype
- IgG
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Indications d'application
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:500,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- BEX2 (Brain Expressed X-Linked 2 (BEX2))
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Autre désignation
- BEX2
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Sujet
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Background: Regulator of mitochondrial apoptosis and G1 cell cycle in breast cancer. Protects the breast cancer cells against mitochondrial apoptosis and this effect is mediated through the modulation of BCL2 protein family, which involves the positive regulation of anti-apoptotic member BCL2 and the negative regulation of pro-apoptotic members BAD, BAK1 and PUMA. Required for the normal cell cycle progression during G1 in breast cancer cells through the regulation of CCND1 and CDKN1A. Regulates the level of PP2A regulatory subunit B and PP2A phosphatase activity.
Aliases: BEX2Protein BEX2 antibody, Brain-expressed X-linked protein 2 antibody, hBex2 antibody
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UniProt
- Q9BXY8
Antigène
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