INTU anticorps (AA 6-139)

N° du produit ABIN7165653

L’anticorps anti-INTU Polyclonal produit chez le Lapin a été validé pour ELISA, IF et IHC. Il convient pour la détection de INTU dans des échantillons provenant de Humain. }

Aperçu rapide pour INTU anticorps (AA 6-139) (ABIN7165653)

Antigène: INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp INTU est non-conjugé

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Détail du produit anti-INTU anticorps

Épitope: AA 6-139

Fonction: INTU Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Protein inturned protein (6-139AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur INTU

Antigène: INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))

Autre désignation: INTU

Sujet:

Background: Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (PubMed:27158779).

Aliases: Homolog of inturned (X. tropicalis) antibody, INT antibody, intu antibody, Inturned planar cell polarity effector homolog antibody, KIAA1284 antibody, PDZ domain containing 6 antibody, PDZ domain-containing protein 6 antibody, PDZD 6 antibody, PDZD6_HUMAN antibody, PDZK6 antibody

UniProt: Q9ULD6