IWS1 anticorps (AA 570-819)

N° du produit ABIN7165661

Cet anticorps Lapin Polyclonal détecte spécifiquement IWS1 dans WB, ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour IWS1 anticorps (AA 570-819) (ABIN7165661)

Antigène: IWS1 (IWS1 Homolog (IWS1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IWS1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-IWS1 anticorps

Épitope: AA 570-819

Fonction: IWS1 Antibody

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Protein IWS1 homolog protein (570-819AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur IWS1

Antigène: IWS1 (IWS1 Homolog (IWS1))

Autre désignation: IWS1

Sujet:

Background: Transcription factor which plays a key role in defining the composition of the RNA polymerase II (RNAPII) elongation complex and in modulating the production of mature mRNA transcripts. Acts as an assembly factor to recruit various factors to the RNAPII elongation complex and is recruited to the complex via binding to the transcription elongation factor SUPT6H bound to the C-terminal domain (CTD) of the RNAPII subunit RPB1 (POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2) to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription.

Aliases: DKFZp761G0123 antibody, FLJ10006 antibody, FLJ14655 antibody, FLJ32319 antibody, Interacts with Spt6 antibody, iws1 antibody, IWS1 homolog antibody, IWS1-like protein antibody, IWS1_HUMAN antibody, IWS1L antibody, MGC126375 antibody, MGC126376 antibody, OTTHUMP00000162262 antibody, Protein IWS1 homolog antibody

UniProt: Q96ST2