PYHIN1 anticorps (AA 1-245)
Aperçu rapide pour PYHIN1 anticorps (AA 1-245) (ABIN7166880)
Antigène
Voir toutes PYHIN1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-245
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Réactivité croisée
- Humain, Souris
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Purification
- >95%, Protein G purified
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Immunogène
- Recombinant Human Pyrin and HIN domain-containing protein 1 protein (1-245AA)
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Isotype
- IgG
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Indications d'application
- Recommended dilution: WB:1:1000-1:5000,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
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Autre désignation
- PYHIN1
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Sujet
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Background: Major mediator of the tumor suppressor activity of IFN in breast cancer cells. Promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization. Promotes ubiquitination and subsequent degradation of HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.
Aliases: IFIX_HUMAN antibody, Interferon-inducible protein X antibody, Pyhin1 antibody, Pyrin and HIN domain-containing protein 1 antibody
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UniProt
- Q6K0P9
Antigène
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