HBXIP anticorps (AA 1-91)

N° du produit ABIN7167073

Cet anticorps anti-HBXIP est un anticorps Lapin Polyclonal détectant HBXIP dans ELISA et IHC. Adapté pour Humain.

Aperçu rapide pour HBXIP anticorps (AA 1-91) (ABIN7167073)

Antigène: HBXIP (Hepatitis B Virus X-Interacting Protein (HBXIP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HBXIP est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-HBXIP anticorps

Épitope: AA 1-91

Fonction: LAMTOR5 Antibody

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Ragulator complex protein LAMTOR5 protein (1-91AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur HBXIP

Antigène: HBXIP (Hepatitis B Virus X-Interacting Protein (HBXIP))

Autre désignation: LAMTOR5

Classe de substances: Viral Protein

Sujet:

Background: As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. When complexed to BIRC5, interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway. Down-regulates hepatitis B virus (HBV) replication.

Aliases: HBV X interacting protein antibody, HBV X-interacting protein antibody, HBX interacting protein antibody, HBX-interacting protein antibody, hbxip antibody, HBXIP_HUMAN antibody, Hepatitis B virus X interacting protein antibody, Hepatitis B virus X-interacting protein antibody, LAMTOR5 antibody, Late endosomal/lysosomal adaptor MAPK and MTOR activator 5 antibody, MGC71071 antibody, Ragulator complex protein LAMTOR5 antibody, XIP antibody

UniProt: O43504

Pathways: Signalisation PI3K-Akt, Regulation of Cell Size