RanBP3 anticorps (AA 1-250)

N° du produit ABIN7167095

Cet anticorps Lapin Polyclonal détecte spécifiquement RanBP3 dans WB, ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour RanBP3 anticorps (AA 1-250) (ABIN7167095)

Antigène: RanBP3 (RANBP3) (RAN Binding Protein 3 (RANBP3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RanBP3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-RanBP3 anticorps

Épitope: AA 1-250

Fonction: RANBP3 Antibody

Réactivité croisée: Souris

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Ran-binding protein 3 protein (1-250AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RanBP3

Antigène: RanBP3 (RANBP3) (RAN Binding Protein 3 (RANBP3))

Autre désignation: RANBP3

Sujet:

Background: Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export.

Aliases: DKFZp586I1520 antibody, Ran binding protein 3 antibody, Ran-binding protein 3 antibody, RANB3_HUMAN antibody, RanBP3 antibody

UniProt: Q9H6Z4