RAB17 anticorps (AA 1-212)

N° du produit ABIN7167233

Cet anticorps Lapin Polyclonal détecte spécifiquement RAB17 dans WB, ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour RAB17 anticorps (AA 1-212) (ABIN7167233)

Antigène: RAB17 (RAB17, Member RAS Oncogene Family (RAB17))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB17 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-RAB17 anticorps

Épitope: AA 1-212

Fonction: RAB17 Antibody

Réactivité croisée: Souris

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Ras-related protein Rab-17 protein (1-212AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RAB17

Antigène: RAB17 (RAB17, Member RAS Oncogene Family (RAB17))

Autre désignation: RAB17

Sujet:

Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in transcytosis, the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. Mainly observed in epithelial cells, transcytosis mediates for instance, the transcellular transport of immunoglobulins from the basolateral surface to the apical surface. Most probably controls membrane trafficking through apical recycling endosomes in a post-endocytic step of transcytosis. Required for melanosome transport and release from melanocytes, it also regulates dendrite and dendritic spine development (By similarity). May also play a role in cell migration.

Aliases: AW413472 antibody, FLJ12538 antibody, OTTHUMP00000164417 antibody, OTTHUMP00000202805 antibody, Rab 17 antibody, Rab17 antibody, RAB17 member RAS oncogene family antibody, RAB17_HUMAN antibody, Ras related protein Rab 17 antibody, Ras related protein Rab17 antibody, Ras-related protein Rab-17 antibody

UniProt: Q9H0T7