RPRD1B anticorps (AA 2-172)

N° du produit ABIN7167582

L’anticorps anti-RPRD1B Polyclonal Lapin est utilisé pour la détection de RPRD1B dans des échantillons de Humain. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour RPRD1B anticorps (AA 2-172) (ABIN7167582)

Antigène: RPRD1B (Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPRD1B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-RPRD1B anticorps

Épitope: AA 2-172

Fonction: RPRD1B Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Regulation of nuclear pre-mRNA domain-containing protein 1B protein (2-172AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RPRD1B

Antigène: RPRD1B (Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B))

Autre désignation: RPRD1B

Sujet:

Background: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. Transcriptional regulator which enhances expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading through the 3\' end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation.

Aliases: RPRD1B antibody, C20orf77 antibody, CREPT antibody, Regulation of nuclear pre-mRNA domain-containing protein 1B antibody, Cell cycle-related and expression-elevated protein in tumor antibody

UniProt: Q9NQG5