RPE65 anticorps (AA 348-484) (HRP)

N° du produit ABIN7167827

Cet anticorps Lapin Polyclonal détecte spécifiquement RPE65 dans ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour RPE65 anticorps (AA 348-484) (HRP) (ABIN7167827)

Antigène: RPE65 (Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPE65 est conjugé à/à la HRP

Application: ELISA

Détail du produit anti-RPE65 anticorps (HRP)

Épitope: AA 348-484

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Retinoid isomerohydrolase protein (348-484AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RPE65

Antigène: RPE65 (Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))

Autre désignation: RPE65

Sujet:

Background: Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT. The enzymatic activity is linearly dependent of the expression levels and membrane association.

Aliases: All-trans-retinyl-palmitate hydrolase antibody, LCA 2 antibody, LCA2 antibody, Leber congenital amaurosis antibody, mRPE 65 antibody, mRPE65 antibody, p63 antibody, rd 12 antibody, rd12 antibody, Retinal pigment epithelium specific 61 kDa protein antibody, Retinal pigment epithelium specific 65 kDa protein antibody, Retinal pigment epithelium specific protein antibody, Retinal pigment epithelium specific protein 65 kDa antibody, Retinal pigment epithelium-specific 65 kDa protein antibody, Retinitis pigmentosa 20 antibody, Retinoid isomerohydrolase antibody, Retinol isomerase antibody, RP 20 antibody, RP20 antibody, RPE 65 antibody, RPE65 antibody, RPE65_HUMAN antibody, sRPE 65 antibody, sRPE65 antibody

UniProt: Q16518