ARHGEF5 anticorps (AA 433-507)

N° du produit ABIN7167986

Cet anticorps Lapin Polyclonal détecte spécifiquement ARHGEF5 dans ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour ARHGEF5 anticorps (AA 433-507) (ABIN7167986)

Antigène: ARHGEF5 (rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGEF5 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-ARHGEF5 anticorps

Épitope: AA 433-507

Fonction: ARHGEF5 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Rho guanine nucleotide exchange factor 5 protein (433-507AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ARHGEF5

Antigène: ARHGEF5 (rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5))

Autre désignation: ARHGEF5

Sujet:

Background: Guanine nucleotide exchange factor which activates Rho GTPases (PubMed:15601624). Strongly activates RHOA (PubMed:15601624). Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1 (By similarity). Involved in regulation of cell shape and actin cytoskeletal organization (PubMed:15601624). Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia (PubMed:14662653). Required for SRC-induced podosome formation (By similarity). Involved in positive regulation of immature dendritic cell migration (By similarity).

Aliases: ARHG5_HUMAN antibody, ARHGEF 5 antibody, ARHGEF5 antibody, DKFZp686N1969 antibody, ephexin 3 antibody, Ephexin-3 antibody, GEF 5 antibody, GEF5 antibody, Guanine nucleotide regulatory protein TIM antibody, Oncogene TIM antibody, P60 antibody, p60 TIM antibody, Rho guanine nucleotide exchange factor (GEF) 5 antibody, Rho guanine nucleotide exchange factor 5 antibody, TIM 1 antibody, TIM antibody, TIM1 antibody, Transforming immortalized mammary oncogene antibody

UniProt: Q12774