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RNF11 anticorps (AA 1-154)

RNF11 Reactivité: Humain ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7168238
  • Antigène Voir toutes RNF11 Anticorps
    RNF11 (Ring Finger Protein 11 (RNF11))
    Épitope
    • 7
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-154
    Reactivité
    • 36
    • 19
    • 18
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 34
    • 3
    Lapin
    Clonalité
    • 35
    • 2
    Polyclonal
    Conjugué
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RNF11 est non-conjugé
    Application
    • 36
    • 16
    • 14
    • 13
    • 13
    • 6
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC)
     Réactivité croisée
    Humain
    Purification
    Antigen Affinity Purified
    Immunogène
    Recombinant Human RING finger protein 11 protein (1-154AA)
    Isotype
    IgG
    Top Product
    Discover our top product RNF11 Anticorps primaire
  • Indications d'application
    Recommended dilution: IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    RNF11 (Ring Finger Protein 11 (RNF11))
    Autre désignation
    RNF11 (RNF11 Produits)
    Synonymes
    anticorps SID1669, anticorps Sid1669, anticorps rnf11, anticorps rnf11-a, anticorps zgc:114095, anticorps zgc:63861, anticorps ring finger protein 11, anticorps ring finger protein 11 L homeolog, anticorps ring finger protein 11b, anticorps ring finger protein 11a, anticorps RNF11, anticorps Rnf11, anticorps rnf11.L, anticorps rnf11b, anticorps rnf11a
    Sujet

    Background: Essential component of a ubiquitin-editing protein complex, comprising also TNFAIP3, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. Promotes the association of TNFAIP3 to RIPK1 after TNF stimulation. TNFAIP3 deubiquitinates \\\'Lys-63\\\' polyubiquitin chains on RIPK1 and catalyzes the formation of \\\'Lys-48\\\'-polyubiquitin chains. This leads to RIPK1 proteasomal degradation and consequently termination of the TNF- or LPS-mediated activation of NF-kappa-B. Recruits STAMBP to the E3 ubiquitin-ligase SMURF2 for ubiquitination, leading to its degradation by the 26S proteasome.

    Aliases: CGI 123 antibody, RING finger protein 11 antibody, RNF11 antibody, RNF11_HUMAN antibody, Sid 1669 antibody, SID1669 antibody

    UniProt
    Q9Y3C5
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