NAT10 anticorps (AA 909-1025) (HRP)

N° du produit ABIN7168286

Cet anticorps Lapin Polyclonal détecte spécifiquement NAT10 dans ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour NAT10 anticorps (AA 909-1025) (HRP) (ABIN7168286)

Antigène: NAT10 (N-Acetyltransferase 10 (GCN5-Related) (NAT10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NAT10 est conjugé à/à la HRP

Application: ELISA

Détail du produit anti-NAT10 anticorps (HRP)

Épitope: AA 909-1025

Fonction: NAT10 Antibody, HRP conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human RNA cytidine acetyltransferase protein (909-1025AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur NAT10

Antigène: NAT10 (N-Acetyltransferase 10 (GCN5-Related) (NAT10))

Autre désignation: NAT10

Sujet:

Background: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs (PubMed:25653167). Catalyzes the formation of N(4)-acetylcytidine (ac4C) at positions 1337 and 1842 in 18S rRNA (By similarity). Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis (PubMed:25653167). Catalyzes the formation of ac4C in serine and leucine tRNAs (By similarity). Requires the tRNA-binding adapter protein THUMBD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation (PubMed:25653167). Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division (PubMed:14592445, PubMed:17631499, PubMed:18082603, PubMed:19303003).

Aliases: ALP antibody, DKFZp434C116 antibody, FLJ10774 antibody, FLJ12179 antibody, FLJ23850 antibody, hALP antibody, KIAA1709 antibody, N acetyltransferase 10 antibody, N acetyltransferase 10 GCN5 related antibody, N acetyltransferase like antibody, N acetyltransferase like protein antibody, N-acetyltransferase 10 antibody, NAT10 antibody, NAT10_HUMAN antibody, NET43 antibody

UniProt: Q9H0A0