MOV10L1 anticorps (AA 336-425)

N° du produit ABIN7168291

Cet anticorps anti-MOV10L1 est un anticorps Lapin Polyclonal détectant MOV10L1 dans WB, ELISA, IHC et IF. Adapté pour Humain.

Aperçu rapide pour MOV10L1 anticorps (AA 336-425) (ABIN7168291)

Antigène: MOV10L1 (Mov10l1, Moloney Leukemia Virus 10-Like 1 (MOV10L1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MOV10L1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-MOV10L1 anticorps

Épitope: AA 336-425

Fonction: MOV10L1 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human RNA helicase Mov10l1 protein (336-425AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MOV10L1

Antigène: MOV10L1 (Mov10l1, Moloney Leukemia Virus 10-Like 1 (MOV10L1))

Autre désignation: MOV10L1

Sujet:

Background: ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the primary piRNA metabolic process. Specifically binds to piRNA precursors and promotes the generation of intermediate piRNA processing fragments that are subsequently loaded to Piwi proteins. Acts via its ATP-dependent RNA helicase activity: displays 5\\\'-3\\\' RNA unwinding activity and probably mediates unwinding and funneling of single-stranded piRNA precursor transcripts to the endonuclease that catalyzes the first cleavage step of piRNA processing to generate piRNA intermediate fragments that are subsequently loaded to Piwi proteins.

Aliases: Cardiac helicase activated by MEF2 protein antibody, Cardiac specific RNA helicase antibody, CHAMP antibody, Csm antibody, M10L1_HUMAN antibody, Moloney leukemia virus 10 like protein 1 antibody, Moloney leukemia virus 10-like protein 1 antibody, MOV10 like 1 antibody, MOV10 like protein 1 antibody, MOV10-like protein 1 antibody, MOV10L1 antibody, Mov10l1, Moloney leukemia virus 10 like 1, homolog (mouse) antibody, Putative helicase Mov10l1 antibody

UniProt: Q9BXT6