RRM1 anticorps

N° du produit ABIN7168449

L’anticorps Souris Monoclonal anti-RRM1 a été validé pour ELISA et IHC. Il convient pour détecter RRM1 dans des échantillons de Humain.

Aperçu rapide pour RRM1 anticorps (ABIN7168449)

Antigène: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RRM1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Clone: 3D6H5

Détail du produit anti-RRM1 anticorps

Réactivité croisée: Humain

Purification: Protein G purified

Immunogène: Recombinant Human RRM1 Protein

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution:IHC:1:50-1:500,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RRM1

Antigène: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Autre désignation: RRM1

Sujet:

Background: This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells.It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor,rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.

Aliases: Ribonucleotide Reductase M1,RRM1,RR1

UniProt: P23921

Pathways: Positive Regulation of Endopeptidase Activity