CD163 anticorps (AA 801-940)

N° du produit ABIN7168618

Cet anticorps anti-CD163 est un anticorps Lapin Polyclonal détectant CD163 dans ELISA et IF. Adapté pour Humain.

Aperçu rapide pour CD163 anticorps (AA 801-940) (ABIN7168618)

Antigène: CD163

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD163 est non-conjugé

Application: ELISA, Immunofluorescence (IF)

Détail du produit anti-CD163 anticorps

Épitope: AA 801-940

Fonction: CD163 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Scavenger receptor cysteine-rich type 1 protein M130 protein (801-940AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CD163

Antigène: CD163

Autre désignation: CD163

Sujet:

Background: Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH -dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells.

Aliases: C163A_HUMAN antibody, CD 163 antibody, CD163 antibody, CD163 antigen antibody, CD163 Molecule antibody, Hemoglobin scavenger receptor antibody, M130 antibody, M130 antigen precursor antibody, Macrophage associated antigen antibody, MM130 antibody, OTTHUMP00000238617 antibody, OTTHUMP00000238618 antibody, OTTHUMP00000238619 antibody, OTTHUMP00000238620 antibody, SCARI1 antibody, Scavenger receptor cysteine rich type 1 protein M130 antibody, sCD163 antibody, Soluble CD163 antibody

UniProt: Q86VB7