SLFN11 anticorps (AA 670-821) (Biotin)

N° du produit ABIN7168623

L’anticorps Lapin Polyclonal anti-SLFN11 a été validé pour ELISA. Il convient pour détecter SLFN11 dans des échantillons de Humain.

Aperçu rapide pour SLFN11 anticorps (AA 670-821) (Biotin) (ABIN7168623)

Antigène: SLFN11 (Schlafen Family Member 11 (SLFN11))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLFN11 est conjugé à/à la Biotin

Application: ELISA

Détail du produit anti-SLFN11 anticorps (Biotin)

Épitope: AA 670-821

Fonction: SLFN11 Antibody, Biotin conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Schlafen family member 11 protein (670-821AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SLFN11

Antigène: SLFN11 (Schlafen Family Member 11 (SLFN11))

Autre désignation: SLFN11

Sujet:

Background: Interferon (IFN)-induced antiviral protein which acts as an inhibitor of retrovirus protein synthesis. Specifically abrogates the production of retroviruses such as human immunodeficiency virus 1 (HIV-1) by acting as a specific inhibitor of the synthesis of retroviruses encoded proteins in a codon-usage-dependent manner. Binds to tRNAs and exploits the unique viral codon bias towards A/T nucleotides. The exact inhibition mechanism is unclear: may either sequesters tRNAs, prevents their maturation via post-transcriptional processing or accelerates their deacylation. Does not inhibit reverse transcription, integration or production and nuclear export of viral RNA. May play a role in cell cycle arrest and/or induction of apoptosis in response to exogenously induced DNA damage.

Aliases: SLFN11 antibody, Schlafen family member 11 antibody, EC 3.6.-.- antibody

UniProt: Q7Z7L1