SLFN11 anticorps (AA 670-821) (FITC)
Aperçu rapide pour SLFN11 anticorps (AA 670-821) (FITC) (ABIN7168624)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 670-821
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Fonction
- SLFN11 Antibody, FITC conjugated
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Purification
- Protein G purified
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Pureté
- >95 %
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Immunogène
- Recombinant Human Schlafen family member 11 protein (670-821AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SLFN11 (Schlafen Family Member 11 (SLFN11))
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Autre désignation
- SLFN11
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Sujet
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Background: Interferon (IFN)-induced antiviral protein which acts as an inhibitor of retrovirus protein synthesis. Specifically abrogates the production of retroviruses such as human immunodeficiency virus 1 (HIV-1) by acting as a specific inhibitor of the synthesis of retroviruses encoded proteins in a codon-usage-dependent manner. Binds to tRNAs and exploits the unique viral codon bias towards A/T nucleotides. The exact inhibition mechanism is unclear: may either sequesters tRNAs, prevents their maturation via post-transcriptional processing or accelerates their deacylation. Does not inhibit reverse transcription, integration or production and nuclear export of viral RNA. May play a role in cell cycle arrest and/or induction of apoptosis in response to exogenously induced DNA damage.
Aliases: SLFN11 antibody, Schlafen family member 11 antibody, EC 3.6.-.- antibody
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UniProt
- Q7Z7L1
Antigène
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