STK24 anticorps (AA 1-431) (Biotin)
Aperçu rapide pour STK24 anticorps (AA 1-431) (Biotin) (ABIN7168983)
Antigène
Voir toutes STK24 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 1-431
-
Fonction
- STK24 Antibody, Biotin conjugated
-
Purification
- Protein G purified
-
Pureté
- >95 %
-
Immunogène
- Recombinant Human Serine/threonine-protein kinase 24 protein (1-431AA)
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
-
Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C,-80 °C
-
Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- STK24 (serine/threonine Kinase 24 (STK24))
-
Autre désignation
- STK24
-
Sujet
-
Background: Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on \'Thr-442\' and stimulates its kinase activity. Regulates cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12. May act as a key regulator of axon regeneration in the optic nerve and radial nerve.
Aliases: epididymis secretory protein Li 95 antibody, HEL-S-95 antibody, Mammalian STE20 like protein kinase 3 antibody, Mammalian STE20-like protein kinase 3 antibody, Mammalian STE20-like protein kinase 3 C-terminal antibody, Mammalian STE20-like protein kinase 3 N-terminal antibody, Mammalian sterile 20-like 3 antibody, MST-3 antibody, MST3/C antibody, MST3/N antibody, MST3B antibody, serine threonine kinase 24 antibody, Serine/threonine kinase 24 (Ste20, yeast homolog) antibody, Serine/threonine-protein kinase 24 12 kDa subunit antibody, Serine/threonine-protein kinase 24 antibody, STE20 homolog yeast antibody, STE20 like kinase MST3 antibody, STE20-like kinase MST3 antibody, Stk24 antibody, STK24_HUMAN antibody, STK3 antibody
-
UniProt
- Q9Y6E0
Antigène
-