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PAK3 anticorps (AA 70-190)

PAK3 Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7169128
  • Antigène Voir toutes PAK3 Anticorps
    PAK3
    Épitope
    • 15
    • 8
    • 8
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 70-190
    Reactivité
    • 70
    • 29
    • 18
    • 3
    Humain
    Hôte
    • 65
    • 5
    • 2
    Lapin
    Clonalité
    • 67
    • 6
    Polyclonal
    Conjugué
    • 33
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PAK3 est non-conjugé
    Application
    • 60
    • 39
    • 31
    • 13
    • 13
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
     Réactivité croisée
    Humain, Souris
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Serine/threonine-protein kinase PAK 3 protein (70-190AA)
    Isotype
    IgG
    Top Product
    Discover our top product PAK3 Anticorps primaire
  • Indications d'application
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    PAK3
    Autre désignation
    PAK3 (PAK3 Produits)
    Synonymes
    anticorps CDKN1A, anticorps MRX30, anticorps MRX47, anticorps OPHN3, anticorps PAK3beta, anticorps bPAK, anticorps hPAK3, anticorps PAK-3, anticorps Pak65alpha, anticorps Pak65beta, anticorps Stk4, anticorps beta-PAK, anticorps XPak3, anticorps bpak, anticorps cdkn1a, anticorps mrx30, anticorps mrx47, anticorps ophn3, anticorps pak3, anticorps pak3-A, anticorps pak3beta, anticorps p21 (RAC1) activated kinase 3, anticorps p21 protein (Cdc42/Rac)-activated kinase 3, anticorps p21 protein (Cdc42/Rac)-activated kinase 3 L homeolog, anticorps PAK3, anticorps Pak3, anticorps pak3.L
    Sujet

    Background: Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. Plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates MAPK4 and MAPK6 and activates the downstream target MAPKAPK5, a regulator of F-actin polymerization and cell migration. Additionally, phosphorylates TNNI3/troponin I to modulate calcium sensitivity and relaxation kinetics of thin myofilaments. May also be involved in early neuronal development.

    Aliases: PAK3 antibody, OPHN3 antibody, Serine/threonine-protein kinase PAK 3 antibody, EC 2.7.11.1 antibody, Beta-PAK antibody, Oligophrenin-3 antibody, p21-activated kinase 3 antibody, PAK-3 antibody

    UniProt
    O75914
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