VRK1 anticorps (AA 257-396)

N° du produit ABIN7169217

L’anticorps Lapin Polyclonal anti-VRK1 a été validé pour WB, IHC et ELISA. Il convient pour détecter VRK1 dans des échantillons de Humain.

Aperçu rapide pour VRK1 anticorps (AA 257-396) (ABIN7169217)

Antigène: VRK1 (Vaccinia Related Kinase 1 (VRK1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VRK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-VRK1 anticorps

Épitope: AA 257-396

Fonction: VRK1 Antibody

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Serine/threonine-protein kinase VRK1 protein (257-396AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur VRK1

Antigène: VRK1 (Vaccinia Related Kinase 1 (VRK1))

Autre désignation: VRK1

Sujet:

Background: Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates \\\'Thr-18\\\' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm. Phosphorylates ATF2 which activates its transcriptional activity.

Aliases: MGC117401 antibody, MGC138280 antibody, MGC142070 antibody, PCH1 antibody, PCH1A antibody, Serine/threonine protein kinase VRK1 antibody, Serine/threonine-protein kinase VRK1 antibody, Vaccinia related kinase 1 antibody, Vaccinia virus B1R related kinase 1 antibody, Vaccinia-related kinase 1 antibody, VRK1 antibody, VRK1_HUMAN antibody

UniProt: Q99986