SLC38A9 anticorps (AA 1-119)

N° du produit ABIN7169972

Détail du produit anti-SLC38A9 anticorps

Antigène: SLC38A9 (Solute Carrier Family 38, Member 9 (SLC38A9))

Épitope: AA 1-119

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC38A9 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Sodium-coupled neutral amino acid transporter 9 protein (1-119AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SLC38A9

Antigène: SLC38A9 (Solute Carrier Family 38, Member 9 (SLC38A9))

Autre désignation: SLC38A9 (SLC38A9 Produits)

Synonymes: anticorps MGC81406, anticorps 4833412L08Rik, anticorps 6720411P22Rik, anticorps 9130023D20Rik, anticorps 9430067K09Rik, anticorps A730092C09, anticorps RGD1311881, anticorps solute carrier family 38 member 9, anticorps solute carrier family 38 member 9 L homeolog, anticorps solute carrier family 38, member 9, anticorps SLC38A9, anticorps slc38a9.L, anticorps slc38a9, anticorps Slc38a9

Sujet:

Background: Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acids. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids (PubMed:25561175, PubMed:25567906). Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of amino acids with low capacity and specificity with a slight preference for polar amino acids, suggesting that it acts as an amino acid sensor instead (PubMed:25561175, PubMed:25567906). The high concentration of arginine in lysosomes suggests that it acts as an arginine sensor (PubMed:25567906).

Aliases: FLJ46104 antibody, FLJ90709 antibody, Homo sapiens solute carrier family 38, member 9 antibody, MGC120544 antibody, OTTHUMP00000161835 antibody, Putative sodium coupled neutral amino acid transporter 9 antibody, Putative sodium-coupled neutral amino acid transporter 9 antibody, Putative uncharacterized protein FLJ90709 antibody, S38A9_HUMAN antibody, SLC38A9 antibody

UniProt: Q8NBW4