SNX17 anticorps (AA 280-457) (Biotin)

N° du produit ABIN7170365

Détail du produit anti-SNX17 anticorps (Biotin)

Antigène: SNX17 (Sorting Nexin 17 (SNX17))

Épitope: AA 280-457

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNX17 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Sorting nexin-17 protein (280-457AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SNX17

Antigène: SNX17 (Sorting Nexin 17 (SNX17))

Autre désignation: SNX17 (SNX17 Produits)

Synonymes: anticorps snx17, anticorps MGC53167, anticorps MGC69341, anticorps MGC198061, anticorps MGC83142, anticorps SNX17, anticorps wu:fb67g03, anticorps wu:fb67g09, anticorps wu:fc27g08, anticorps wu:fj81d04, anticorps si:ch211-101l18.2, anticorps 5830447M19Rik, anticorps AI790646, anticorps D5Ertd260e, anticorps mKIAA0064, anticorps sorting nexin 17, anticorps sorting nexin 17 L homeolog, anticorps snx17, anticorps SNX17, anticorps snx17.L, anticorps Snx17

Sujet:

Background: Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Recycles internalized integrins ITGB1, ITGB5 and their associated alpha subunits, preventing them from lysosomal degradation. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)).

Aliases: Similar to a putative C elegans gene encoded in cosmid F17H10 antibody, Snx17 antibody, SNX17_HUMAN antibody, Sorting nexin 17 antibody, Sorting nexin-17 antibody

UniProt: Q15036