SPAG5 anticorps (AA 1-300)

N° du produit ABIN7170478

Cet anticorps anti-SPAG5 est un anticorps Lapin Polyclonal détectant SPAG5 dans WB, ELISA et IHC. Adapté pour Humain.

Aperçu rapide pour SPAG5 anticorps (AA 1-300) (ABIN7170478)

Antigène: SPAG5 (Sperm Associated Antigen 5 (SPAG5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPAG5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-SPAG5 anticorps

Épitope: AA 1-300

Fonction: SPAG5 Antibody

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Sperm-associated antigen 5 protein (1-300AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SPAG5

Antigène: SPAG5 (Sperm Associated Antigen 5 (SPAG5))

Autre désignation: SPAG5

Sujet:

Background: Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase. Required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. In complex with SKAP, promotes stable microtubule-kinetochore attachments. May contribute to the regulation of separase activity. May regulate AURKA localization to mitotic spindle, but not to centrosomes and CCNB1 localization to both mitotic spindle and centrosomes. In non-mitotic cells, upon stress induction, inhibits mammalian target of rapamycin complex 1 (mTORC1) association and recruits the mTORC1 component RPTOR to stress granules (SGs), thereby preventing mTORC1 hyperactivation-induced apoptosis. May enhance GSK3B-mediated phosphorylation of other substrates, such as MAPT/TAU.

Aliases: Astrin antibody, Deepest antibody, hMAP 126 antibody, hMAP126 antibody, MAP 126 antibody, MAP126 antibody, Mitotic spindle associated protein antibody, Mitotic spindle associated protein p126 antibody, Mitotic spindle coiled coil related protein antibody, Mitotic spindle-associated protein p126 antibody, SPAG 5 antibody, SPAG5 antibody, SPAG5_HUMAN antibody, Sperm associated antigen 5 antibody, Sperm tail protein Spag 5 antibody, Sperm tail protein Spag5 antibody, Sperm-associated antigen 5 antibody

UniProt: Q96R06

Pathways: M Phase