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Spindlin 1 anticorps (AA 1-262)

SPIN1 Reactivité: Humain WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7170599
  • Antigène Voir toutes Spindlin 1 (SPIN1) Anticorps
    Spindlin 1 (SPIN1)
    Épitope
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-262
    Reactivité
    • 22
    • 12
    • 12
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 22
    Lapin
    Clonalité
    • 22
    Polyclonal
    Conjugué
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Spindlin 1 est non-conjugé
    Application
    • 14
    • 9
    • 8
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
     Réactivité croisée
    Humain
    Purification
    Antigen Affinity Purified
    Immunogène
    Recombinant Human Spindlin-1 protein (1-262AA)
    Isotype
    IgG
  • Indications d'application
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    Spindlin 1 (SPIN1)
    Autre désignation
    SPIN1 (SPIN1 Produits)
    Synonymes
    anticorps SPIN, anticorps AA553322, anticorps AA673430, anticorps Spin, anticorps spin, anticorps spindlin, anticorps MGC115436, anticorps Spindlin-1, anticorps DKFZp459K085, anticorps spindlin 1, anticorps spindlin 1 L homeolog, anticorps SPIN1, anticorps Spin1, anticorps spin1, anticorps spin1.L
    Sujet

    Background: Chromatin reader that specifically recognizes and binds histone H3 both trimethylated at \\\'Lys-4\\\' and asymmetrically dimethylated at \\\'Arg-8\\\' (H3K4me3 and H3R8me2a) and acts as an activator of Wnt signaling pathway dowstream of PRMT2. In case of cancer, promotes cell cancer proliferation via activation of the Wnt signaling pathway (PubMed:24589551). Overexpression induces metaphase arrest and chromosomal instability. Localizes to active rDNA loci and promotes the expression of rRNA genes (PubMed:21960006). May play a role in cell-cycle regulation during the transition from gamete to embryo. Involved in oocyte meiotic resumption, a process that takes place before ovulation to resume meiosis of oocytes blocked in prophase I: may act by regulating maternal transcripts to control meiotic resumption.

    Aliases: OCR antibody, Ovarian cancer-related protein antibody, SPIN antibody, Spin1 antibody, SPIN1_HUMAN antibody, Spindlin-1 antibody

    UniProt
    Q9Y657
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